Lobular Carcinoma in Situ (LCIS)

Lobular Carcinoma in Situ (LCIS)

LCIS is a fairly rare condition that results from the formation of abnormal cells in the milk ducts and lobules of the breast. Although lobular carcinoma in situ is not breast cancer and does not develop into cancer, women with LCIS have an estimated 20 percent increased risk of developing invasive breast cancer in the future.
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Signs and Symptoms of Lobular Carcinoma in Situ

Unlike other breast abnormalities, LCIS does not typically produce obvious symptoms, and does not usually appear on a mammogram. Many women often learn that they have lobular carcinoma in situ as a secondary result of a biopsy or screening for an unrelated lump or breast abnormality. Although LCIS usually does not produce noticeable symptoms, Dr. Khan advises women to be vigilant for any changes to the breasts, including:

  • Nipple discharge
  • Lumps
  • Thickening or puckering of skin
  • Any changes in the texture or appearance of the skin of the breast or nipple

Risk Factors for Lobular Carcinoma in Situ

Because LCIS is a rare condition and the direct causes are unclear, diagnosing and predicting the condition can be difficult unless women and their doctors are aware of what to look for. Some of the factors that can increase the likelihood or risk of developing LCIS include:

Family history of breast cancer – Women with one or more close relatives diagnosed with breast cancer may be at a higher risk of developing lobular carcinoma in situ.

Hormone replacement therapy for menopause – Hormone replacement therapy treatments for women in menopause (used for more than three to five years) could potentially increase the risk of LCIS.

Age – While there is no set rule, more women in the early 40s age range that have not undergone menopause are typically diagnosed with LCIS. However, the condition is becoming more common in women who have undergone menopause as well.


Treating Lobular Carcinoma in Situ

Treatment for LCIS will vary from patient to patient depending on a number of factors, such as a woman’s personal preference and individual risk levels for developing invasive breast cancer in the future. After an LCIS diagnosis, a breast specialist may recommend regular screening and surveillance to monitor changes in the breasts, medication (also known as preventive therapy), or surgery, depending on the woman’s family history and individual risk levels.

Breast Cancer Screening and Risk Assessment

Understanding your family history and individual risk levels for developing breast cancer is the first step in managing your health. To learn more about your risk for LCIS and to schedule a breast cancer screening, contact Dr. Sadia Khan today at (949) 860-7357 to schedule a consultation.


Contact a Breast Cancer Specialist Today

For compassionate, professional diagnosis and treatment for breast cancer, do not hesitate to contact Dr. Sadia Khan, a fellowship-trained breast surgeon at Hoag Breast Care Center in Newport Beach. Please call 949.390.9381 to schedule a comprehensive consultation today!



Next, read about Flat Epithelial Atypia (FEA).